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Cell viability experiments All experiments examining the effects of p53 activation or RNR inhibition on cell death used a pretreatment phase (24 or 48 h)

2 Adherence remains challenging

In recent years, increased awareness of low energy availability (LEA) and its downstream consequences, including Relative Energy Deficiency in Sport (REDs), has reshaped conversations around body weight, recovery, injury risk, and long-term athlete development

GLP-1s and DKA GLP-1s have quickly become infamous for their bad gastrointestinal side effects

Patients should be informed that incretin therapy for lipedema represents off-label use with uncertain benefits specific to lipedema tissue

6 This shift was in response to previously approved T2D medications subsequently demonstrating neutral or harmful cardiovascular effects