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This pathway begins with the binding of CP to reduced glutathione (GSH) by the action of the glutathione-S-transferase (GST) enzyme in circulation (Miller et al., 2010

References Chen XJ, Liu DY, et al

The amino acid sequence of the active peptide is identical both are modified GHRH (1-29) analogs with four amino acid substitutions (Ala2, Gln8, Ala15, Leu27) that improve enzymatic stability

Nicholson C, Sykova E

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