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GLP-1/GIP has reportedly help people lose 22% of their weight
The model includes the fixed class effects of treatment, strata (pooled country/geographic region, baseline OSA severity and gender), visit and treatment-by-visit interaction, as well as the continuous, fixed covariate of baseline value
Clinical trials have indicated that GLP-1 RAinduced weight loss in older adults can result in measurable reductions in lean mass, with the proportion of lean tissue loss varying depending on the specific GLP-1 RA, dose, treatment duration, and concurrent lifestyle interventions (see Table 1)
(235), and its decreased content may cause higher oxidative stress in the thyroid (235)
However, the trade-offs are significant longer recovery time, more bruising, and typically the need for general anesthesia
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