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Previous studies show that irisin can mitigate -synuclein-induced neurodegeneration in the preformed fibril (PFF) mouse model of sporadic PD 15

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They work through different mechanisms (GLP-1 and GIP receptor activation) and are FDA-approved prescription medications for type 2 diabetes and/or obesity management

Sarah Carstens is the addictions clinical director of Outpatient Services at Penn Medicines Princeton House Behavioral Health