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Several SURMOUNT studies in patients with obesity are ongoing ( In the SURPASS-1 study, which enrolled 705 non-target T2DM patients with diet and physical activity intervention, the efficacy, safety, and tolerability of tirzepatide and a placebo were compared
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This may be more prevalent in the control group, leading to a reduced differential of weight loss between the control and intervention arm
Therefore, focal inflammatory foci correlate well with the observed functional indices of mild hepatocellular leakiness as detected by increased serum enzyme levels
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