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A few small human trials have been conducted, primarily for inflammatory bowel disease
How soon will I feel more energetic after a B12 injection
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Excess cobalamin in the blood showed barely detectable binding to TC II (Andrs et al., 2013)
For example, long-term use of proton pump inhibitors (PPIs) or metformin can affect B12 absorption by altering stomach acidity or interfering with normal absorption processes
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