Furthermore, it was also responsible of in vitro endothelial cells conversion into a pro-inflammatory phenotype, characterized by increased expression of tissue factor, thrombin-activatable fibrinolysis inhibitor and plasminogen activator inhibitor [65]
ILA inhibits the polarization of mouse Th17 cells in vitro and stimulates the secretion of IL-22 by lamina propria lymphocytes through activation of the aryl hydrocarbon receptor (AhR), thereby promoting the proliferation of intestinal epithelial cells and repairing damaged intestinal mucosa (94)
At maintenance doses of 1.0mg to 2.4mg weekly, a 5mg vial lasts only two to five weeks
Journal of biomedical research
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