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The Evidence: "GLP-1 peptide is 100% homologous between cats and humans, making incretin-based therapies physiologically viable for feline patients." This homology is crucial
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In a 48-week phase II clinical trial conducted on patients with type 2 diabetes and obesity, treatment with a dose of 10 mg/kg of bimagrumab resulted in a significant reduction in fat mass by 20.5% (compared to 0.5% in the placebo group), while lean body mass increased by 3.6% (as opposed to a decrease of 0.8% in the placebo group), leading to an overall body weight reduction of -6.5%, which was substantially better than the -0.8% observed in the placebo group
The synthesis of this chemically versatile tripeptide occurs in two ATP-dependent steps (Figure 1
Non ci sono ancora studi clinici sufficienti per poter stabilire che luso della carnitina come integratore sia sicuro in gravidanza e in stato di allattamento
