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Wegovy and Zepbound moved GLP-1 therapy into chronic weight management, creating a direct challenge to older anti-obesity drugs that often delivered limited efficacy or poor tolerability

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Finally, with an understanding of cellular events subsequent to NAPQI, the rationale for potential therapies like fomepizole that may prevent or attenuate hepatocyte death long after NAPQI formation will be addressed

Regulators may consider GLP-1 references as a disease-re lated or health-related claim