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While DSIP also seemed to encourage the growth of prolactin-producing cells, this might not be a direct result of DSIPs action

Moreover, the ferroptosis-related proteins GPX4 and xCT were markedly decreased, and oxidative stress was markedly induced in the liver of MS rats

Therefore, accelerated oxidation of biomolecules acts both as a product and causal for disease manifestation which is further exacerbated by failure of antioxidant system and loss of redox sensing capabilities of chaperone DJ-1 18,19

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In addition, a one- or two-step DOC can be considered for properly selected low-risk patients