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Oxidized Glutathione (GSSG): This is the "spent" state
These reference points come from preclinical literature and small pilots
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Moreover, these multi-protein complexes are continuously exposed to a GSH-depleted environment in Gclc -deficient FoB, which might alter protein folding or their targeting to the mitochondria
OConnor K, Russell K, Tucker A, BunnellB, Lacey M, Andreeff M
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