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The kinetic constants (K M and V max ) were obtained according to MichaelisMenten equation: V = V max [S]/(K M + [S]) (1), where V was the initial velocity, [S] was the concentration of the substrate, K M was the MichaelisMenten constant, and V max was the maximal reaction velocity

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Since soluble urate, xanthine oxidase inhibitor treatment, and free fatty acids modulate inflammation, our findings suggest that by suppressing lipolysis, ULT could regulate inflammation in gout and comorbid metabolic and cardiovascular disease