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In a Phase 2b obesity trial , AOD-9604 did not produce statistically significant weight loss versus placebo , and pharmaceutical development was discontinued around 2007 [3] [4]
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[5] Altered sleep patterns, difficulty concentrating, irritability, overactivity, excitability, mental depression, confusion and impaired judgement have all been reported in patients receiving 15 mg of folic acid daily for 1 month
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