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And you can argue that maybe with now the generics becoming available as patents are expiring, that will change anyways

For example, about 17% of people reported getting more respect or attention after one month on the medication, compared to over 50% of those who had been taking it for at least four months

Ferrndiz L, Ojeda-Vila T, Corrales A, Martn-Gutirrez FJ, Ruz-de-Casas A, Galdeano R, o lvarez-Torralba I, et al (2017) Internet-based skin cancer screening using clinical images alone or in conjunction with dermoscopic images: a randomized teledermoscopy trial

or cancer has spread to one lymph node on the same side of the body as the tumor, the affected node is larger than 3 centimeters, and cancer has spread through to the outside covering of the lymph node

In the trial, the average weight loss amongst all participants, regardless of whether they reduced their dose, had side effects, or dropped out of the trial, was 13.6%