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What we have is an enormous amount of anecdotal reporting, mostly from athletes and biohackers who've used it for injury recovery, combined with animal data that's mechanistically compelling

It should avoid consumer-facing phrases, outcome language, and claims that go beyond published model-specific evidence

Its sometimes used alongside treatment for depression and anxiety

Patients should be informed of the pros and cons of oral versus parenteral therapy, and regardless of the form of treatment, those with pernicious anemia or malabsorption should be reminded of the need for lifelong replacement

Brain Behav

B12 is water-soluble and generally safe to take with most supplements