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We evaluate pivotal clinical trial data, including SURPASS, SURMOUNT, and STEP program results, highlighting differences in average weight loss, metabolic effects, and tolerability

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Barbagelata L, Masson W, Lobo M, et al

Future research should aim to unravel the precise molecular mechanisms underlying these weight-independent benefits, enabling the development of new therapies that harness these anti-inflammatory pathways and potentially bypass the limitations of current interventions

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