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Save Sodium-Glucose Cotransporter 2 Inhibitors (SGLT2i) and Glucagon-like peptide-1 receptor agonists (GLP1-RA) were initially developed as glucose-lowering agents for the treatment of Type 2 Diabetes

GIP primarily signals through cAMP/Epac2, while GLP-1 uses both cAMP/PKA and cAMP/Epac2 pathways

We dont know yet if it is better or worse, Jay says

Semaglutide binds to GLP-1 receptors in multiple tissues throughout the body, including the pancreas, gastrointestinal tract, and brain

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