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The report was uncontrolled, unblinded, not randomized, had no comparator arm, used patient-reported outcomes rather than validated pain instruments, and did not publish dose, effect size, confidence intervals, p-values, or systematically collected adverse events limitations that severely constrain any clinical inference

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(Photo: Getty Images) On April 26, 58-year-old ultramarathoner, podcaster, and bowhunting influencer Cameron Cam Hanes ran 2:39:11 in the Eugene Marathon, winning the masters division

Oral: Shorter systemic half-life, longer local GI effect SubQ/IM Injection: Longer systemic presence, especially with IM use 3

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