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Up to now, no adequate and well-controlled reproduction studies have been conducted in humans and animals to determine its effects on pregnant women (17)

If the patient is suspected to be sensitive to cobalt or other components of cobalamin, an intradermal test dose is recommended.[12][15] Several laboratory tests should be performed prior to treatment with cyanocobalamin, including serum vitamin B12, folate, iron, hematocrit, and reticulocyte count

High-Risk Groups Older Adults Aging impacts B12 absorption, increasing deficiency rates to over 20% in seniors