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A recent study showed that PPT1 regulates systemic autoimmunity by removing S-palmitoylation from C258 and C265 of TLR9 in lysosomes, promoting the secretion of TNF by macrophages in systemic lupus erythematosus ( 151 )

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Its also worth noting that excess selenium can lead to increased oxidative stress rather than relieve it, so consume no more than 400 micrograms of selenium per day