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In the 1800s, Jarisch-Herxheimer reactions were first described by Adolf Jarisch in medical literature after he noticed a worsening of skin lesions in a patient who had begun treatment for syphilis
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However, by putting the lidocaine in with the filler, were able to avoid those additional injections for numbing, and this lower dose of lidocaine wears off much faster, so youre not fully numb for several hours after
As with any pharmacological therapy, it is important that GLP-1 and GIP therapy is given to those who are most likely to benefit
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