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A hallmark of autophagy is the generation of double-membraned autophagosomes, which subsequently fuse with either an endosome or a lysosome to enable degradation (143)

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The Ala-Glu-Asp sequence appears to influence osteoblasts via mechanisms similar to those in chondrocytes, supporting mineralization

Facilitates cellular energy production through improved mitochondrial function

Upon FCCP treatment, the ETC activity rate increases in the attempt to restore the proton gradient and re-couple it to OXPHOS

3 Disruption of carnitine availability leads not only to impaired fatty acid metabolism, but also to clinical manifestations