Effect of a 3-month L-carnitine supplementation and resistance training program on circulating markers and bone mineral density in postmenopausal women: a randomized controlled trial
Careful control of these parameters can modulate the interactions between nanomaterials and biological tissues, including their penetration, diffusion, absorption, distribution, immune recognition, retention time in organs, and systemic clearance, thereby minimizing unintended toxic effects (176)
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It's dictated by the compound's molecular stability, tissue distribution kinetics, and the precision required to detect dose-dependent effects
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