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Personalized dosing strategies: Not every patient needs the maximum dose

In adults with growth hormone receptor deficiency, eight weeks of rhIGF-1 therapy significantly increased whole-body protein synthesis, decreased protein oxidation and increased lean body mass while reducing fat mass, demonstrating enhanced muscle anabolism and nutrient utilization in humans

This method reduces side effects and allows for more gradual progress

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So they actively assign people to either the drug or the placebo to help control other possible causes