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This regulatory effect helps preserve collagen integrity, maintain epithelial barriers, and reduce inflammation-driven degradation associated with aging and chronic stress

These signaling pathways lead to the production of different sets of pro-inflammatory cytokines, respectively, via NF-B transcription factor pathway activation, and via MAP kinases phosphorylation and subsequent activation of type I PI3-kinase/Akt and transcription factors AP-1 and CREB [24]

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7 Disordered sperm production by the testes can result in low sperm numbers or defects in sperm morphology (size, shape, and structure) that can contribute to infertility

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