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Deiodinases (DIOs) regulate thyroid hormone metabolism by catalyzing the conversion of thyroid hormones from precursor thyroxine (T 4 ) to biologically active triiodothyronine (T 3 ) or inactive reverse T 3 (rT 3 ) 54
In animal studies, it has been associated with faster healing of tendons, ligaments, and muscles, possibly through effects on angiogenesis and growth-factor signaling
MaYWangCElmhadiMZhangHLiuFGaoXet al
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For researchers interested in tissue repair , muscle protein synthesis , or fat metabolism , understanding this IGF-1 pathway becomes essential for setting realistic expectations and designing effective protocols
May your metabolic health stay optimized, your weight management stay sustainable, and your supplement choices stay evidence-based.
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