10.1104/pp.103.035956 141 VadasseryJ.TripathiS.PrasadR.VarmaA.OelmllerR
Schlechte HH, Schnorr D, Loning T, Rudolph BD, Pohrt UM, Loening SA
Peptide Vials (BPC-157 + TB-500, 10 mg blend each): 8 weeks 4 vials 12 weeks 6 vials 16 weeks 8 vials Insulin Syringes (U-100): Per week: 7 syringes (1/day) 8 weeks: 56 syringes 12 weeks: 84 syringes 16 weeks: 112 syringes Bacteriostatic Water (10 mL bottles): Use 3.0 mL per vial for reconstitution
High doses do not compensate for a poor delivery system
499 Sareptas SRP-5051, an ASO conjugated with a targeting peptide, has shown higher levels of dystrophin expression and exon skipping rates than eteplirsen
Maestri, A., De Pasquale, Ceratti A., Cundari, S., Zanna, C., Cortesi, E., and Crino, L