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While neither cagrilintide nor retatrutide has been studied exclusively in male populations, available trial data include substantial numbers of male participants

2 What to eat when appetite is low When appetite is low, prioritize protein, enough total food, and hydration before you worry about perfect meals

Some patients may benefit from transitioning to lower doses of GLP-1 medications rather than complete discontinuation, though this approach requires further research to establish optimal dosing strategies

Second Natures peer-reviewed research directly compared both medications when combined with behavioural support, finding Mounjaro users lost 22.1% of their starting weight while Wegovy (up to 2.4 mg) users lost 17.1% at 12 months

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Without adequate protein, you lose muscle along with fat, which slows your metabolism and makes weight regain more likely after stopping medication