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Volek's recovery study (PMID 11788381) deliberately used a three-week loading period before its exercise challenge an acknowledgment that the first week is preparation, not payoff

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Deletion of cyclooxygenase-2 in the mouse increases arterial blood pressure with no impairment in renal NO production in response to chronic high salt intake

Trends in Endocrinology & Metabolism , 33 (1), 18-35