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(Accessed 2025) for general background and side effect incidence from Phase 3 trials
Insulinotropin: Glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas
Its certainly plausible, in the same way that other medications that help with appetite, such as topiramate, have utility. The problem, said Steinglass, who also serves as director of research at the Eating Disorders Research Clinic, is that large studies of GLP-1 RAs for obesity and diabetes have not included individuals with psychiatric illnesses or EDs, leaving critical gaps in knowledge about their effects in these populations
12 Therefore, managing diet involves leveraging the positive aspect of fullness while avoiding choices that exacerbate discomfort due to this slowed digestion
But now, advocates fear these drugs may continue to be out of reach for many
