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Hence, the results of the meta-analysis may indicate reduced vagal modulation in ME/CFS, along with increased sympathetic modulation of heart rate (329)

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This process is marked by a substantial accumulation of ROS, triggered through the activation of the KEAP1PGAM family member 5, mitochondrial serine/threonine protein phosphatase (PGAM5)AIFM1 signaling cascade (Fig

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