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These senescent cell clearance research findings have significant implications for anti-aging intervention development, chemotherapy recovery support, and understanding how cellular senescence contributes to age-related tissue dysfunction and disease pathogenesis
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Comparative metaproteomics analysis shows altered fecal microbiota signatures in patients with major depressive disorder
Autophagy dysregulation is involved in the pathophysiology of DKD by increasing ROS production, mediating inflammatory responses and inducing renal cell damage and apoptosis (116, 117)
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MAMs are essential for the regulation of the neuronal Ca 2+ concentration via the SERCA, the ER channels inositol 1,4,5-trisphosphate receptors, the glucose-regulated protein 75, the MCU, and the voltage-dependent anion channel (VDAC) [61]
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