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Khojasteh-Bakht SC et al
[PMID: 11222940] PubMed record related to this compound for laboratory literature review
The levels of p-STAT3 and STAT3 significantly increase, leading to overexpression of cyclooxygenase-2 (COX-2) and COX-2 mRNA, indicating that H 2 S can decrease cell apoptosis through the STAT3/COX-2 signaling pathway and promote the progression of HCC
Over time, oxidative stress, inflammation, and disease risk increase
Glutathione antioxidant effects include glutathione peroxidase-catalyzed reactions with the removal of hydrogen peroxide, organic peroxides, and peroxynitrite