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Some versions add green tea, lemon juice, or apple cider vinegar for extra flavor or supposed benefits

Abbreviations: AMI: acute myocardial infarction

GLP-1 receptor agonists are known to affect pulse rate [42] and, accordingly, when semaglutide was compared head-to-head with another once-weekly GLP-1 receptor agonist, exenatide extended release, the elevation in pulse rate was not significantly different [26]

The researchers detected no significant interaction by sex, although the study may have been underpowered to identify sex-related differences

It is the most widely studied of the three, with extensive clinical trial data supporting its efficacy for weight management