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Non-steroidal anti-inflammatory drugs (NSAIDs), commonly used for pain relief, are well-established causes of gastric and duodenal ulceration and should be used cautiously in this population

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How DPP-4 Works DPP-4 cleaves two amino acids from the N-terminus of GLP-1, converting the active hormone GLP-1(7-36) into an inactive fragment GLP-1(9-36)

These contain high levels of fructose or sorbitol that ferment readily in a slow-moving gut