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For example, alterations in monoaminergic systems such as serotonin and dopamine may contribute to both anxiety and depression, and neurodegeneration in the prefrontal cortex may lead to both aggression and depression

Thats where glutathione supplementation comes in

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Overexpression of MDM2 results in decreased level and activity of p53 (Kubbutat et al, 1997) and provides an alternative to a p53 mutation in the sense that it inactivates p53

All reported ALS cases were defined by the diagnosis of possible, probable or definite ALS according to the revised El Escorial criteria by an experienced neurologist

Polymorphisms affecting GST have been documented to exert significant modulatory effects on the biological cascade of carcinogenesis and have been discussed vigorously in the literature