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The principal research objective of this multicenter double-blinded randomized placebo controlled trial was to determine the dose required to achieve physiological melatonin blood levels in preterm infants, similar to that of the mother and to define its pharmacokinetic profile in preterm infants

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A 2022 paper in Aging characterised that epitalon protected against post-ovulatory aging-related damage of mouse oocytes in vitro (PMID 35413689), framing one route by which the compound engages reproductive-aging research

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