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In these populations, discontinuation of GLP-1RAs before or during early pregnancy has been associated with greater gestational weight gain and, in some reports, less favorable pregnancy-related metabolic outcomes

1 Orthostatic hypotension, bradycardia, and syncope also can occur, especially with rapid clozapine titration

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Bioavailability: Why Injection Outperforms Oral Administration Bioavailability is the fraction of an administered dose that reaches systemic circulation in active form

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Smith, E.J