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In addition, Src-dependent Cav-1 phosphorylation is a crucial process mediating caveolae-associated endocytosis and eNOS activation in vascular endothelial cells 24,25

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These observations are in contrast to previous findings in the same Nrf2-GFP-HepG2 reporter model exposed to DEM or tert -butylhydroquinone, which indicate a lower Nrf2 response toward repeated treatments (Bischoff et al