Syam M, Hasan HY, Emad S, Sayed AEA, A AH, Ibrahim AS (2020) Girinimbine from curry leaves promotes gastro protection against ethanol induced peptic ulcers and improves healing via regulation of anti-inflammatory and antioxidant mechanisms
acetaldehyde also directly impairs gonadal steroidogenesis
in Cell Metabolism note that SIRT1 activation improves mitochondrial efficiency and promotes a shift toward lipid utilization for energy, which can be especially beneficial in endurance and fat-loss settings (Price et al., Cell Metabolism )
J Immunol 166:40424048 Mohan S, Abdelwahab SI, Cheah SC, Sukari MA, Syam S, Shamsuddin N, Rais Mustafa M (2013) Apoptosis effect of girinimbine isolated from Murraya koenigii on lung cancer cells in vitro
Injectable administration provides higher bioavailability and systemic effects
Based on the above analysis, gut microbiota-regulated BCAAs drive mTORC1-mediated muscle lipid accumulation and insulin resistance in high-fat diet-induced obesity