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Some individuals experience mild gastrointestinal effects including nausea or abdominal discomfort, particularly with higher doses or when first initiating therapy

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Lancet Diabetes Endocrinol 6(8):605617 Tuttle KR, Lakshmanan MC, Rayner B, Busch RS, Zimmermann AG, Woodward DB et al (2018b) Dulaglutide versus insulin glargine in patients with type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7): a multicentre, open-label, randomised trial

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Inhibiting SNX9 blocks harmful MDV formation, restores mitochondrial dynamics, and rescues healing in diabetic mice, positioning MDVs as promising therapeutic targets (Zhang H