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Sodium-glucose co-transporter-2 (SGLT-2) inhibitors and cancer: a meta-analysis of randomized controlled trials

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The G protein-coupled receptor of GLP-1 (GLP-1R) originally identified in islet -cells is widely expressed in extrapancreatic tissues as well including the lungs, kidney, brain, the enteric and peripheral nervous system, lymphocytes, smooth muscle cells (SMCs), and atrial cardiomyocytes [32] The specific identity of GLP-1 receptor-positive (GLP-1R+) cells in the heart remains uncertain

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In bacterial pathogens, furin-activated toxins may promote tissue invasion, increase transmission rates, or suppress cellular immune responses 338

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Takeuchi et al, 1993)

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