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For severe deficiency, the AAFP recommends loading doses typically daily or every other day for one to two weeks followed by monthly maintenance injections

[3] Dosing of hydroxocobalamin should be individualized based on the severity of vitamin B deficiency and clinical response

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Inherited disorders of folate and cobalamin transport and metabolism (updated chapter in OMMBID)

Tangible Benefits Elevating NAD+ levels can influence several aspects of physical and cognitive performance

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