If side effects persist, PlexusDx providers can consider oral tirzepatide, dose reduction, or a return to semaglutideall flat-rate options with no price adjustment
These GLP-1 drugs have proven effective at helping people lose weightand are showing promise for a host of other indications, including heart disease and liver disease
Meet our doctors Last reviewed: 19 Jun 2026 Sources Glucagon-like peptide-1 (GLP-1): a gut hormone of potential interest in the treatment of diabetes (1998) PubMed [accessed 21 October 2025] Wegovy dosing schedule (2024) Wegovy.com [accessed 21 October 2025] Wegovy (semaglutide): a new weight loss drug for chronic weight management (2022) BMJ [accessed 21 October 2025] Wegovy 0.25 mg, FlexTouch solution for injection in pre-filled pen (2023) EMC [accessed 13 January 2026] Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes, The New England Journal of Medicine [accessed 21 October 2025] Weight loss injections NHS weight loss injections GLP-1 for weight loss Can doctors help with weight loss
In clinical trials, participants are provided with exercise support and access to dietitians and psychologists
We see professionals who feel drained after long weeks, parents who want more consistent energy, and active adults who notice that recovery and focus are not what they used to be
Eating smaller, frequent meals of bland, low-fat foods