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[23] Patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency should avoid topical dapsone concentrations 5 % owing to the rare but serious risk of dose-dependent hemolytic anemia, particularly if extensive surface area is treated or occlusion is used
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On top of that, the SURPASS-3 MRI sub study showed that a substantial fraction of the lean mass lost on tirzepatide was intramuscular fat, not muscle tissue
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