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This age-related decline is one of the most frequently cited data points in copper-peptide research literature, and its a primary reason GHK-Cu is studied within the broader context of cellular aging and peptides for longevity research rather than treated purely as a wound-healing or dermatology compound

Results Analysis showed that 96 h of treatment with glutathione led to an increase in the expression levels of genes encoding phenylalanine ammonia-lyase (PAL), cinnamyl alcohol dehydrogenase (CAD) and peroxidase (POD)

& Wang, Y

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Raja 2012

Onto that scaffold the LR3 construct adds two changes