Patients should be counselled about the importance of adherence to their maintenance schedule
Reported timelines come from compound-level research and community use
The use of proton pump inhibitors (PPIs) has been associated with an increased risk of vitamin B12 deficiency, particular in older adults and those on long-term PPI therapy. Nutrition Reviews Duration-Dependent Risk Assessment The risk of B12 deficiency from PPIs grows with time
B12 deficiencies are usually a result of diet, especially among vegans, this is because we can only get vitamin b12 through foods such as meat, fish and dairy products, our bodies do not produce it
Sterility and preservative concentration are only warranted up to that date
Cyclic/Sequential Estradiol Therapy: For Women Still Menstruating When labs and symptoms suggest late perimenopause with declining estrogen (low-normal estradiol, elevated FSH, vasomotor symptoms), sequential hormone therapy may be appropriate [21,22]