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References Orlovius AK, Thomas A, Schnzer W, Thevis M

GLP-1 receptor agonists work by mimicking GLP-1, a naturally occurring hormone involved in blood sugar regulation and appetite signaling

This population faces a higher risk of B12 deficiency which may be further increased by use of acid-reducing medications

So if someone is low in B12 and they consume alcohol, they not only don't have enough B12 to help 'clear away' the alcohol toxins but they also risk increasing homocysteine levels which I believe is that feeling of heat/hangover that can persist when there isn't enough B12 to reset the body

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[PMID: 38043870] PubMed record related to this compound for laboratory literature review