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Carly A

Target 1.0 to 1.2 grams of protein per pound of goal body weight daily

No drugs in development currently target nuclear export specifically

The injectable agents are listed as likely low instead, based on high molecular weight and very high protein binding

In this context, GLP-1 receptor agonists represent one of the most promising pharmacological classes, particularly if challenges related to cost, equitable access, reimbursement policy, and supply constraints are addressed

For many patients, gastric sleeve is one of the strongest GLP-1 alternatives because it offers more durable weight loss, reduces hunger, and avoids the ongoing monthly cost of medication