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Taking the medication with food, staying hydrated, eating smaller portions, and using anti-nausea medication during peak weeks (6-8) dramatically improves tolerability

Because of this variability, clinicians sometimes adjust dose pacing or escalation strategy when working with women in perimenopause and menopause

Peptide drugs like semaglutide are notoriously difficult to deliver orally

That story is painful because it mistakes a biology problem for a character flaw